Pathophysiology of Early Vascular Ageing-Opportunities for Treatment

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Pathophysiology of Early Vascular Ageing-Opportunities for Treatment

The story of vascular ageing was first described in the seventeenth century when Thomas Sydenham wrote that ‘A man is as old as his arteries’. This aphorism was returned to publicity lately when Peter Nilsson reintroduced the concept of early vascular ageing. As vascular ageing is described a gradual process involving biochemical, enzymatic, and cellular changes of the vasculature and modificat...

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Ageing and vascular ageing.

There is an age related decline in various physiological processes. Vascular ageing is associated with changes in the mechanical and the structural properties of the vascular wall, which leads to the loss of arterial elasticity and reduced arterial compliance. Arterial compliance can be measured by different parameters like pulse wave velocity, augmentation index, and systemic arterial complian...

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ژورنال

عنوان ژورنال: The Open Hypertension Journal

سال: 2013

ISSN: 1876-5262

DOI: 10.2174/1876526201305010058